Deposits

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      {
        "id": "13",
        "title": "Report Of The Scientific Committee Of The Spanish Agency For Food Safety And Nutrition (Aesan) On The Role Of Nutrition In Autoimmune Diseases.",
        "type": "Report",
        "description": "<p>The immune system is a network of cells, tissues, and organs that work together to defend the body <br>\nagainst attacks by “foreign” invaders. If pathogens survive the body’s front-line defenses, they still <br>\nhave to find a way to escape a series of general defenses of the innate immune system, which are ready to attack without regard for specific antigen markers. These include patrolling phagocytes, natural killer T cells, and complement. Pathogens that cross the general barriers then confront specific weapons <br>\nof the adaptive immune system tailored just for them. (...) These tissues form the gut-associated lymphoid tissue and include the tonsils, adenoids, Peyer´s patches, lymphoid aggregates and appendix. (...) The result is called an <br>\nautoimmune disease. (...) The profound effect of diet on the immune system is well-known since many years ago. (...) In this regard, it has been established that: i) it is not yet possible to conclude whether caloric restriction improves the pathology of human autoimmune diseases; ii) polyunsaturated fatty acids seem to reduce autoimmune disease severity, however, its mechanisms of action is still unclear; iii) some dietary peptides and proteins are capable of inducing autoimmune diseases, such as celiac disease, type 1 diabetes and rheumatoid arthritis; iv) human studies investigating the effects of antioxidant vitamins, administered alone or together, have shown not quite significant benefits on clinical symptoms; v) vitamin D deficiency is associated with a higher risk of type 1 diabetes and multiple sclerosis. Deficiency <br>\nsupplementation ameliorates this predisposition and vi) the few randomised, double-blind placebocontrolled <br>\ntrials, with high doses of several probiotics strains, carried on patients with inflammatory bowel diseases, show a decrease in clinical inflammatory score, in medically treated patients. (...)</p>",
        "identifier": "10.5281/zenodo.808030",
        "subject": [
          "autoimmune diseases",
          "Opinion",
          "Spain",
          "nutrients",
          "nutrition",
          "immune system",
          "probiotics"
        ],
        "rightsholder": [
          "Spanish Agency for Consumer Affairs, Food Safety and Nutrition"
        ],
        "creator": [
          "Spanish Agency for Consumer Affairs, Food Safety and Nutrition"
        ],
        "issued": "2011-04-01T00:00:00Z",
        "publisher": "Zenodo",
        "rights": [
          "Creative Commons Attribution 4.0",
          "Open Access"
        ],
        "relation": [
          "10.5281/zenodo.808029"
        ],
        "source": "http://doi.org/10.5281/zenodo.808030"
      },
      {
        "id": "14",
        "title": "Report Of The Scientific Committee Of Aesan In Relation To The Microbiological Risks Associated With The Consumption Of Fruits Obtained From Fragaria And Rubus Spp.",
        "type": "Report",
        "description": "<p>The consumption and as a result, the world production of fruits obtained from Fragaria spp. (such as <br>\nstrawberries) or Rubus spp. (such as raspberries or blackberries) has significantly increased worldwide <br>\nin recent years. Spain is one of the largest producers of fruits from these plants, such as strawberries <br>\nand raspberries. It is therefore of great relevance to know the microbiological risks associated with the <br>\nconsumption of these fruits, as well as the possible preventive measures to avoid the occurrence of <br>\noutbreaks derived from berries intake. <br>\nTo the present, these fruits have caused outbreaks mainly due to the presence of viral agents <br>\n(especially norovirus and hepatitis A virus) and parasites (especially Cyclospora cayetanensis), whereas <br>\nin the case of bacterial pathogens it has only been documented one outbreak caused by Escherichia <br>\ncoli O157: H7. <br>\nGiven the heterogeneity of potentially contaminating pathogens in these products, and the fact that <br>\nthey are usually eaten raw or minimally processed, it is difficult to establish disinfection protocols to <br>\nensure their safety. For this reason, in order to maintain food security it is essential to maximize the <br>\ngood hygienic practices in cultivation and harvesting, especially in fruits cultivated at ground level. <br>\nIt is also necessary to maintain a standardized and internationally accepted traceability system that <br>\nallows a rapid identification of the causing agent when an outbreak caused by the consumption of <br>\nthese fruits occurs.</p>",
        "identifier": "10.5281/zenodo.807935",
        "subject": [
          "foodborne diseases",
          "Opinion",
          "disinfection",
          "foodborne",
          "blackberries",
          "raspberries",
          "Spain",
          "microbiological risks",
          "outbreak",
          "strawberries",
          "outbreaks",
          "prevention"
        ],
        "rightsholder": [
          "Spanish Agency for Consumer Affairs, Food Safety and Nutrition"
        ],
        "creator": [
          "Spanish Agency for Consumer Affairs, Food Safety and Nutrition"
        ],
        "issued": "2013-02-01T00:00:00Z",
        "publisher": "Zenodo",
        "rights": [
          "Creative Commons Attribution 4.0",
          "Open Access"
        ],
        "relation": [
          "10.5281/zenodo.807934"
        ],
        "source": "http://doi.org/10.5281/zenodo.807935"
      },
      {
        "id": "17",
        "title": "Report Of The Scientific Committe Of Aesan About The Safety Criteria Applicable To The Content Of Domoic Acid In Scallops (Pecten Maximus) Harvesting",
        "type": "Report",
        "description": "<p>Commission Decision 2002/226/EC of 15 March 2002 (UE, 2002) allows a restricted harvesting regime  <br>\nof scallops with a domoic acid concentration in the whole body higher than 20 mg/kg. For this, two consecutive analyses of samples, taken between one and seven days maximum, must show that  <br>\nthe domoic acid concentration in the whole mollusk is lower than 250 mg/kg and that the DA concentration  <br>\nin the parts intended for human consumption (muscle + gonad), which have to be analyzed separately, is lower than 4.6 mg/kg.  <br>\nThe Autonomous Community of Galicia proposes to include the analysis of muscle + gonad (the  <br>\nedible part) as a basis for the checks of the harvesting in production areas, while maintaining the  <br>\nsame reference level of 4.6 mg/kg.  <br>\nThis Committee considers that the level of 4.6 mg/kg for the edible part (muscle + gonad) is safe  <br>\nand can be used as a criterion in the checks of the harvesting of scallop.</p>",
        "identifier": "10.5281/zenodo.807099",
        "subject": [
          "Opinion",
          "Spain",
          "amnesic",
          "amendment of the Decision 2002/226/EC",
          "shellfish",
          "King scallop",
          "poisoning",
          "Pecten spp.",
          "legal limit",
          "Domoic acid"
        ],
        "rightsholder": [
          "Spanish Agency for Consumer Affairs, Food Safety and Nutrition"
        ],
        "creator": [
          "Spanish Agency for Consumer Affairs, Food Safety and Nutrition"
        ],
        "issued": "2009-10-01T00:00:00Z",
        "publisher": "Zenodo",
        "rights": [
          "Creative Commons Attribution 4.0",
          "Open Access"
        ],
        "relation": [
          "10.5281/zenodo.807098"
        ],
        "source": "http://doi.org/10.5281/zenodo.807099"
      }
    ]
  }
}